When exploring the mechanism of SCFA, it was found that the basic level of glucagon-like peptide (GLP)-1 in mice with knocked out G protein-coupled receptor (GPR)-43 was reduced by nearly 43%, and the levels of peptide YY and GLP-1 in the gut were still decreased after propionate administration (54)
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Figure 3 The stratified analysis was performed by analysing only the trials that used a placebo group as comparator, When the trials were analysed according to the different dosing schemes (subcutaneous vs
[DOI] [PubMed] [Google Scholar] 65.Lee Y.S., Shin S., Shigihara T., Hahm E., Liu M.J., Han J., Yoon J.W., Jun H.S